American Heart Association Awards $15 Million to Study Women's Cardiovascular-Kidney-Metabolic Health

The American Heart Association has awarded $15 million to research teams from Augusta University, Massachusetts General Hospital, and The Ohio State University to study cardiovascular-kidney-metabolic (CKM) syndrome in women. The four-year project will explore why women may be more susceptible to certain health risks across different life stages.

CKM syndrome encompasses the combined health effects of heart disease, kidney disease, diabetes, and obesity. Approximately one in three U.S. adults experiences at least three components of this syndrome, including high blood pressure, abnormal cholesterol, high blood glucose, impaired kidney function, and excess body weight.

Each research center will focus on unique aspects of women's health. Augusta University will investigate obesity's lifelong effects, examining weight gain differences between males and females and potential pregnancy complications. Massachusetts General Hospital will study how pregnancy history and female-specific risk factors might predict future heart disease. The Ohio State University will explore personalized medical treatments and community support programs targeting women's cardiovascular health.

A critical component of the research is addressing the historical underrepresentation of women in clinical studies. By understanding biological variations, life cycle impacts, and societal factors, researchers hope to develop more targeted preventive strategies and therapeutic approaches specifically designed for women.

The project also emphasizes diversity in clinical research, with each center collaborating with academic institutions serving underrepresented populations. This approach aims to create comprehensive insights into women's cardiovascular health across different demographic groups.