The American Heart Association's Get With The Guidelines - Heart Failure program has dramatically transformed heart failure patient care over nearly two decades, significantly reducing mortality rates and improving treatment protocols across hundreds of U.S. hospitals.
Research published in Circulation: Heart Failure reveals that hospitals participating in the program consistently outperform their peers in heart failure process measures and patient outcomes. When the program launched in 2005, approximately one in three heart failure patients died within a year. Today, more than 600 hospitals nationwide have implemented evidence-based guidelines that have substantially improved patient survival.
Key improvements include data-driven benchmarking, comprehensive hospital toolkits, professional development workshops, and recognition programs designed to accelerate the adoption of best-practice therapies. The program has not only improved immediate patient care but has also challenged existing medical assumptions, such as previous beliefs about patient prognoses based on left ventricular ejection fraction.
Despite significant progress, medical experts emphasize that challenges remain. Dr. Gregg Fonarow noted that heart failure mortality remains high, and many patients still do not receive optimal evidence-based treatments. The registry has now generated over 170 peer-reviewed publications, serving as a critical research platform for understanding and improving cardiovascular care.
The Get With The Guidelines program represents a transformative approach to healthcare quality improvement, demonstrating how systematic data collection, analysis, and implementation of best practices can meaningfully enhance patient outcomes across complex medical conditions.


