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Kairos Pharma Ltd. Showcases Promising Preclinical Results for KROS101 at ASCO 2025

TL;DR

Kairos Pharma's KROS101 outperforms TRX518 in enhancing T cell activity and reducing immune suppression, offering a competitive edge in cancer immunotherapy.

KROS101, a small molecule GITR ligand agonist, works by boosting effector T cell activity and reducing T reg cells, demonstrating a dual mechanism in preclinical studies.

Kairos Pharma's KROS101 advances cancer treatment by stimulating immune response and tumor destruction, promising a better future for patients worldwide.

Discover how Kairos Pharma's KROS101 is revolutionizing cancer immunotherapy with its unique dual mechanism, showcased at ASCO 2025.

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Kairos Pharma Ltd. Showcases Promising Preclinical Results for KROS101 at ASCO 2025

Kairos Pharma Ltd. (NYSE American: KAPA) has unveiled promising preclinical data for its investigational drug, KROS101, at the ASCO 2025 Annual Meeting. The study highlights KROS101's unique ability to enhance effector T cell activity while diminishing immune-suppressive T reg cells, a dual mechanism that could significantly advance cancer immunotherapy. The drug demonstrated superior performance in promoting tumor infiltration, increasing cytotoxicity, and preventing T cell exhaustion compared to previous treatments.

The implications of these findings are profound for the field of oncology. KROS101's ability to simultaneously stimulate the immune system and target tumor cells presents a novel approach to overcoming some of the most challenging aspects of cancer treatment, such as drug resistance and immune suppression. This could lead to more effective therapies for patients with hard-to-treat cancers, offering hope where options are currently limited.

Dr. John Yu, CEO of Kairos Pharma, emphasized the significance of these results, noting the potential of KROS101 to redefine cancer treatment paradigms. The data not only underscore the drug's therapeutic potential but also highlight Kairos Pharma's innovative approach to addressing unmet needs in oncology. As the company progresses with its clinical trials, the medical community eagerly anticipates further developments that could bring this promising therapy to patients worldwide.

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