Lifespan Edge, the next-generation longevity clinic co-founded by futurist John Mauldin and preventive medicine pioneer Dr. Michael Roizen, has announced the opening of two new locations in West Palm Beach, Florida, and Columbia, Maryland, with a third premier destination planned for Scottsdale, Arizona. This expansion marks another milestone in the company's mission to make personalized, evidence-based longevity care more accessible.
Founded in 2024, Lifespan Edge was created to bridge cutting-edge longevity research with individualized clinical care for individuals seeking to optimize healthspan, cognitive vitality, and quality of life. “Healthcare should not begin when disease appears, it should begin decades earlier,” said Dr. Michael Roizen, Chair of the Board and Co-Founder of Lifespan Edge. “Our goal is to help people understand that many of the factors influencing how they age are modifiable. Through personalized care, informed lifestyle choices, and emerging scientific advances, we believe individuals can take greater control of their long-term health.”
The new locations include 2528 Okeechobee Blvd. in West Palm Beach, Florida, and 10700 Charter Drive, Suite 200, in Columbia, Maryland. Each clinic is designed to provide a concierge-style experience that combines advanced diagnostics, physician-guided evaluations, and personalized strategies focused on prevention, performance, and healthy aging. A third location in Scottsdale, Arizona, is planned as a premier luxury wellness destination to serve clients from across the United States and abroad.
Interest in longevity medicine has accelerated as consumers increasingly seek proactive approaches to maintaining cognitive function, metabolic health, physical resilience, and overall vitality. Rather than focusing solely on treating disease after symptoms arise, Lifespan Edge emphasizes identifying risk factors early and creating individualized plans that support long-term wellness. John Mauldin, President and Co-Founder, believes this represents a fundamental evolution in healthcare. “We founded Lifespan Edge because we saw an opportunity to bring together leading physicians, science-driven medicine, and personalized care under one roof,” he said. “As longevity research continues to advance, we want our clinics to help translate that science into practical strategies that empower people to live healthier, more productive lives.”
Among the areas attracting growing scientific interest is Therapeutic Plasma Exchange (TPE), a medical procedure with established clinical uses for certain conditions that is also being investigated for potential applications related to aging and neurodegenerative disease. One notable area of research includes the AMBAR (Alzheimer Management by Albumin Replacement) clinical trial, which evaluated plasma exchange with albumin replacement in patients with mild-to-moderate Alzheimer’s disease. Published findings reported that the intervention showed promise in slowing decline in certain cognitive and functional measures compared with controls, while investigators emphasized that additional research is needed to better define its role and long-term impact. Reflecting on the broader significance of emerging therapies, Dr. Roizen said, “The most exciting developments in longevity are helping us better understand how the body repairs itself and how interventions may support healthier aging. Our philosophy is to follow the science, personalize care, and continually evaluate new evidence as it emerges.”
Dr. Roizen has long advocated that biological age and chronological age are not always the same, emphasizing that lifestyle choices, including nutrition, physical activity, stress management, purpose, and social connection, can meaningfully influence long-term health. “People have more influence over their future health than they often realize,” he said. “The decisions we make every day - how we move, what we eat, how we manage stress, and the relationships we cultivate - can have profound effects over time.”
With additional locations planned and a continued focus on personalized medicine, Lifespan Edge aims to help redefine what aging can look like in the decades ahead. By bringing together physician expertise, advanced diagnostics, and evolving longevity science, the company seeks to provide individuals with evidence-informed strategies to support longer, healthier, and more active lives. As demand for precision wellness and preventive healthcare continues to rise, Lifespan Edge’s expansion into Florida, Maryland, and soon Arizona represents an important step toward making sophisticated longevity care available to more communities across the country.
The expansion comes amid growing national recognition for its leadership team. Dr. Michael Roizen was recently featured in Entrepreneur and TopDoctor Magazine, where he shared his philosophy that persistence, prevention, and personalized care have the power to reshape healthcare and redefine aging. Lifespan Edge currently operates four locations including Dallas, Texas, and Dorado, Puerto Rico, with Scottsdale coming soon, continuing its mission of bringing science-driven longevity care to more individuals.

