Creative Biogene Expands Antibody Purification Platform to Support Biotechnology Innovation

Creative Biogene has expanded its antibody purification platform to provide a streamlined workflow for producing high-yield, high-purity antibodies through scalable and customizable protocols. The platform refines purification strategies from various expression sources, addressing the growing need for consistent and efficient antibody preparations in biotechnology research and development.

The purification workflow incorporates capture, intermediate, and polishing steps, utilizing Protein A/G/L resins for Fc-binding antibodies, ion exchange chromatography for charge-based purification, and size exclusion chromatography for aggregate removal, ensuring final antibody purity exceeding 95%. The platform also features orthogonal processes including hydrophobic interaction chromatography, multimodal approaches, and buffer exchange. Quality control services include SDS-PAGE, SEC-HPLC, and endotoxin testing, with results delivered in comprehensive Certificate of Analysis reports available at https://www.creative-biogene.com/services/antibody-purification-service.

A comprehensive equipment suite supports the platform, featuring compact, easy-to-operate chromatography columns and process chromatography systems available at laboratory and pilot scales for customizable system design. Buffer dilution and conditioning systems enable precise formulation while reducing resource consumption. Filtration systems, including tangential flow, depth filtration, and single-use options, ensure rapid turnaround between purification runs, providing a complete and flexible solution for antibody production.

The platform serves multiple biotechnology applications, supporting antibody candidate development programs, assay optimization, kit component production, and research reagent manufacturing. According to Marcia Brady's Chief Expert, platform evaluation demonstrated its primary value lies in well-balanced throughput and reproducibility, with optimization ensuring consistent results across various scales and antibody targets, enabling researchers to streamline their workflows effectively.

Creative Biogene plans continued system improvements with enhanced automation features and increased scalability. Through future integration and refinement of purification protocols and scalable design, the company aims to provide comprehensive solutions for current and emerging research needs, supporting the biotechnology industry's advancement with reliable, accessible purification technology at https://www.creative-biogene.com.