Creative Biolabs Launches Advanced Neuroscience Platforms to Address Growing Neurodegenerative Disease Research Needs

By Burstable Editorial Team

TL;DR

Creative Biolabs' new neuroscience tools provide researchers with advanced competitive advantages in drug screening and Alzheimer's disease model development.

Creative Biolabs developed specialized assays using live-cell imaging and co-culture systems to study Schwann cell function and microglial phagocytosis mechanisms.

These neuroscience platforms advance Alzheimer's research, potentially leading to better treatments for the 55 million people worldwide living with dementia.

Creative Biolabs offers real-time visualization of microglial phagocytosis and a webinar on microglia's role in Alzheimer's disease tomorrow.

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Creative Biolabs Launches Advanced Neuroscience Platforms to Address Growing Neurodegenerative Disease Research Needs

Creative Biolabs has unveiled a comprehensive suite of specialized neuroscience platforms designed to accelerate research into neurodegenerative diseases, particularly Alzheimer's disease, which affects millions worldwide. The World Health Organization reports more than 55 million people currently live with dementia globally, with Alzheimer's disease estimated to cause up to 70% of dementia cases, creating an urgent need for advanced research tools.

The company's new Schwann Cell Assay platform represents a significant advancement for peripheral nervous system research. Schwann cells are crucial for axonal regeneration and myelination, and this platform enables isolation of Schwann cells from three species: human, mouse, and rat. The system supports a co-culture environment with neurons, allowing scientists to assess critical functional measures including neurotrophic factor secretion and myelination potential, both essential for regenerative medicine applications.

For central nervous system research, Creative Biolabs introduced its microglia phagocytosis assay service. Microglia serve as the brain's resident immune cells and play vital roles in maintaining neural homeostasis, responding to neuroinflammation, and eliminating pathological protein aggregates. This service utilizes live-cell imaging and fluorescently labelled bioparticles, enabling researchers to visualize microglial phagocytic function in real time, providing unprecedented insight into neuroimmune interactions.

The company has also developed comprehensive preclinical assessment services for Alzheimer's disease models, featuring both 2D and 3D platforms that replicate key disease aspects including amyloid deposition, tauopathy, and neuroinflammation. These models can represent either familial or sporadic forms of Alzheimer's disease and are initiated from patient-derived induced pluripotent stem cells, offering researchers more physiologically relevant contexts for drug screening and mechanistic studies. Researchers can learn more about these advanced solutions at https://neuros.creative-biolabs.com/.

These technological advancements come at a critical time when the global research community faces increasing pressure to develop effective treatments for neurodegenerative diseases. The platforms' ability to provide more accurate cellular models and real-time functional assessments could significantly accelerate drug discovery timelines and improve the translation of basic research findings into clinical applications. The integration of species-specific models and patient-derived cells particularly enhances the relevance of preclinical testing, potentially reducing late-stage drug development failures.

The impact of these platforms extends beyond Alzheimer's research, as the tools and methodologies developed could be adapted for studying other neurological disorders including Parkinson's disease, multiple sclerosis, and various neuroinflammatory conditions. By providing researchers with more sophisticated and physiologically relevant experimental systems, Creative Biolabs' innovations may contribute to breaking longstanding barriers in neuroscience research and ultimately lead to more effective therapeutic interventions for millions affected by neurodegenerative diseases worldwide.

Curated from 24-7 Press Release

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Burstable Editorial Team

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